PET Imaging

Docking Station and Imaging Chamber

Your imaging system should take care of your animal.

PET studies should be about biologically meaningful results, not just instrumentation. A successful experiment depends on successful preparation – you need the right tools to gain flexibility in study design and preparation, streamline workflow, and increase throughput.

Sofie has developed a new approach to small animal prep and management that reduces manual steps and user intervention. With multiple docking stations, induction boxes, and associated imaging chambers, you can image one animal while safely queuing the next.

Docking Station

Simply glide the Imaging Chamber into the Docking Station to automatically deliver heat and anesthesia. These key factors can affect the physiology of your animal, and therefore your data. Regulation of temperature and oxygen are critical to a well-executed study.

  • Automatic anesthesia and heating
  • Efficient animal prep
  • Simplified workflow
  • High-throughput capability
  • Standardized location of mouse for imaging

Imaging Chamber

The ergonomically designed bed slides effortlessly between the docking station and GENISYS4, keeping your animal in a secure, warm, and pathogen-free environment. The curved handle allows for easy carrying, as well as syringe storage during “on the bed” injections for dynamic scans.

  • Nose cone anesthesia and constant heating (37°C)
  • Reproducible positioning of the mouse for imaging
  • Pathogen barrier for environmental protection
  • Provisions
    • Catheter line
    • Blood sampling lines for kinetic studies
    • Slot to hold syringe for dynamic studies
  • Multi-modality connectivity for MRI, CT, SPECT

Real-Time Animal Monitoring

You spend a lot of time validating and preparing your animal model for study – why leave its well-being to chance? GENISYS’ built-in video camera allows researchers to monitor the physiologic condition of their rodent in real-time, taking the guesswork out of anesthesia management for an optimal and safe imaging environment.

GENISYS acquisition software shows the rodent breathing frequency at 97 bpm. On-board camera (not shown) extracts visual information from respiratory movement to calculate and report breathing rate.

OsiriX Image Analysis Software

We’ve partnered with the OsiriX Foundation to bring you the most comprehensive translational image analysis tool available. GENISYS users are able to navigate and visualize multi-modality and multi-dimensional images from both preclinical and clinical data sets on one analysis platform.

Download OsiriX here.

Developed at UCLA for radiologists by radiologists with the charter to create an easy-to-operate open-source alternative to costly DICOM viewers. OsiriX brought diagnostic image analysis to the next level, quickly becoming the most popular software package for MRI, CT, and PET.

The arrival of GENISYS requires a new solution for preclinical image analysis. The Sofie-OsiriX collaboration is an natural extension of both organizations’ efforts to promote molecular imaging in research, enable the widest variety of scientists with imaging tools, and increase the power of PET.
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